Clinical Laboratory Sciences Syllabi


Syllabus for CLLS 5417
Hematology and Coagulation I
Instructor:Leonce H. Thierry, MS, MT(ASCP)CHES
Contact Information:Office: SHP 4.437
Phone: (409) 772-9475
Course Description:

The student will be given the opportunity to demonstrate the ability to: 1) recognize and correlate significant features and processes related to the formation, function, and morphology of the normal cellular elements of the blood; 2) accurately perform basic hematologic procedures and calculations; 3) recognize abnormal hematologic test results; 4) associate certain abnormal results with general disease processes or potential sources of error in the procedure; 5) recognize and respond to procedures used to verify the accuracy of test results; 6) describe the basic components of coagulation/hemostasis; 7) accurately perform basic coagulation testing procedures; 8) recognize sources of error in the performance of coagulation testing; 9) select appropriate coagulation tests to demonstrate specific abnormalities in the hemostatic mechanism;

Course Objectives:

Course Objectives

Successful completion of the course depends on the student’s ability to:
1. Discuss hematopoiesis;
2. Discuss the function of normal cellular elements of blood;
3. Identify the morphological characteristics of both normal and abnormal cellular elements of blood;
4. Perform routine clinical hematological procedures.
5. Define hemostasis.
6. Differentiate the four major components of hemostasis, describing the role of each component and tests used for the evaluation of that component.
7. Discuss the four major processes of hemostasis.
8. Discuss the effect on testing of various sampling problems and running of coagulation tests.
9. Recognize potential problems that would make samples inappropriate for testing.
10. Discuss the interaction of the vasculature, platelets, coagulation factors, and fibrinolysis in normal hemostasis.
11. Describe and differentiate the functional components of the platelets, including the chemicals involved in the hemostatic mechanism.
12. Draw the coagulation cascade, identifying all factors and cofactors and their appropriate placement in the intrinsic, extrinsic, or common pathway.
13. Explain the role of fibrinolysis in maintaining normal hemostasis.
14. Describe and select appropriate test procedures for evaluation of each of the four major components of hemostasis.
15. Interpret results from coagulation tests.

Affective Objectives:

Students will be given the opportunity to demonstrate the development of behaviors and attitudes consistent with those of the profession. Evaluation of these behaviors will be performed using the Affective Objectives and Evaluation checklist in the Orientation Handbook and the outcome of this evaluation will be reflected in the your course grade as part of your participation grade (8%). You will have the opportunity to develop these attributes in classroom assignments and activities. You will be placed in different work groups or assigned different partners for exercises. You will also be given opportunities to demonstrate your ability to work independently, follow instructions and be creative.

Required Course Materials:


Clinical Laboratory Hematology Second Edition. McKenzie: S.B. Prentice Hall. Upper Saddle River NJ (2009)

Clinical Hematology Atlas Third Edition. Carr J.H., Rodak, B.F. Elsevier Saunders. St. Louis MO (2009)

Clinical Laboratory Science The Basics and Routine Techniques 5th Edition. Linne, J.J., Ringsrud, K.M. C.V. Mosby (2007)

Recommended Textbook: Medical Dictionary

Method of Evaluation:

Students should refer to the Department Academic Policies for general information regarding the Attendance, Methods of Evaluation, and Academic Dishonesty.  Those general Policies apply to this course. 

Students must obtain an overall average of 70% or higher in order to satisfactorily complete the course. The grade will be based on the following:

Lecture: 45% of the total course grade will be comprised of the average of the five examination scores. The best five quiz grades will be averaged together to count as one lecture examination grade.

Laboratory: 36% of the total grade will be derived from your laboratory work. Three(3) Practicals will be given and each will count as 6% of the total course grade. The remaining 18% of the laboratory grade will be based on the average of assignments and laboratory participation.

Final Examinations: 19% of the course grade will be based on the grades of the comprehensive final examinations. 10% of the grade will be derived from the final lecture examination and 9% from the final practical exam.

Course Policies:Participation: Students will be expected to attend class, take notes, and participate in class projects. Assignments will not be accepted after the due date. Makeup exams and labs will be given only on selected Fridays with documentation of an illness or acceptable excuse as defined in the CLS Attendance and Participation policy in the Orientation Handbook. It is the student's responsibility to inform the instructor, via email, that a make-up exam or lab is necessary. Not all labs are available for make-up.


General Policies of the School of Health Professions

Academic Progress:Information regarding the Student's academic progress in this course will be shared with their Academic Advisor and/or Department Chair. Student's making unsatisfactory progress will be referred to the Office of Student Affairs for assistance.
Academic Integrity:Academic dishonesty includes, but is not limited to, cheating, plagiarism, collusion, the submission for credit of any work or materials that are attributable in whole or in part to another person, taking an examination for another person, and any act designed to give unfair advantage to a student or the attempt to commit such an act. Procedures to be followed in the event of alleged academic dishonesty are described in the Rules and Regulations of the Board of Regents of The University of Texas System, and the SAHS Student Handbook. Alleged academic dishonesty issues should be reported to the Student Affairs Officer.
Professional Behavior:As a part of a professional program, you are expected to conduct yourselves in a manner consistent with the level of trust and responsibility that will be placed on you when you are part of a health care team. You are expected to be honest in your dealings with your instructor and your peers. You are also expected to be able to follow instructions, to act with the utmost integrity, to follow safety protocols while in laboratory, to perform laboratory work with care, and to act in accordance with those standards characteristic of those we call "professionals."
Behavior during examinations, written and practical, will be monitored. Inappropriate behavior may result in pursuance of disciplinary action.
University Statement on Equality, Tolerance, and Affirmative Action:Please indicate by the end of the second week of the semester if you will need accommodations under the Americans with Disabilities Act (Public Law 101-336). If the need for ADA accommodations should arise during the semester you will need to make your request within one week of returning to classes. You may contact your Instructor or the Office of Student Affairs.
Course Evaluation:Students will be given the opportunity to evaluate the instructor and course near the end of the course/semester. When submitting course evaluations students must follow the guidelines provided by the course instructor or the department.
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