Clinical Laboratory Sciences Syllabi


Syllabus for CLLS 5310
Serology / Blood Bank
Instructor:LeeAnn Walker, MEd; MT(ASCP) SBB
Contact Information:Office: SHP 4.436
Phone: 772-9477
Course Description:The purpose of this class is to focus on principles of the antigen/antibody reactions; innate immunity and inflammation; immunoglobulins; syphilis; the ABO and Rh systems; the antiglobulin technique and compatibility testing. Emphasis will be on the role of the immune system in health and disease as well as the major blood group system in transfusion medicine. The Lecture portion of the course will concentrate on a theoretical understanding of the systems' functions. The Laboratory section will be designed to integrate this information to demonstrate two important principles: (1) How immunologic principals are used in clinical laboratory confirmation or diagnosis. (2) How the major blood group systems and the antiglobulin techniques serve as the basis for transfusion medicine.
Course Objectives:

Upon completion of the this course, the student will be able to:
1. Apply the theoretical concepts of immunological techniques to the evaluation of
specific methodologies;
2. Apply the theoretical concepts of immunological techniques to evaluate the results
obtained when testing patient samples and determine whether these results can be
safely reported;
3. Utilize the theoretical concepts of immunological techniques to determine what
steps need to be taken in resolving technical problems with a test;
4. Determine what the presence of a specific antigen or antibody indicates about the
patient's current status related to a specific disease;
5. Apply knowledge of the antigen and antibody characteristics of blood group systems
in procedures to detect and identify them;
6. Utilize the principles of compatibility testing, and component preparation to select
appropriate donors, determine donor/recipient compatibility, and
7. Perform immunohematological techniques and determine whether the results can be

Affective Objectives:

Students will be given the opportunity to demonstrate the development of behaviors and attitudes consistent with those of the profession. Evaluation of these behaviors will be performed using the Affective Objectives and Evaluation checklist in the Orientation Handbook.

The student should successfully meet these objectives a minimum of 70% of the time for satisfactory completion of this course. Certain criteria on the checklist are more specific. Students must meet those criteria at the level indicated on the checklist.

Required Course Materials:

Textbook: Harmening, D.M.: Modern Blood Banking and Transfusion Practices, 5th Ed. and Stevens, C.D. Clinical Immunology and Serology, 3nd Ed.

Method of Evaluation:
Course Activities and Weighting
Grading Scale


Case Studies/ Participation


90% - 100%


2 Lecture Exams




2 quizzes


70% - 79%


2 Laboratory Exams




Comprehensive Lec. Final


60% - 69%


Comprehensive Lab Final


59% and below






Laboratory unknown may include wet labs to evaluate lab performance:
1. These will be completed independently. You bring only your pen to the bench,
unless you are specifically told you may use a calculator.
2. There will be NEITHER consultation NOR reference material used during the
administration of the unknowns. This includes procedures.
3. Any explanatory or questioning comments to fellow students concerning your
results within the lab will indicate to the instructors that you have chosen to hand in
your unknown for "0" credit.
4. Each unknown is expected to be completed within the regular lab period;
therefore, efficient use of time is required.
5. Any original specimen and ALL tubes are to be kept in your rack at your
workstation upon completion. The results sheet is to be placed face down under the rack.

Course Policies:STUDENT RESPONSIBILITY: Students will be expected to attend class, take notes, and participate in class discussions and laboratory activities. All classes require participation in one form or another. You are expected to come to class on time and ready to participate in designated activities. Due to the structure of most laboratories, make ups may not be possible. If a student misses a class, it is their responsibility to get handouts and notes. Makeup tests will be given only if prior approval has been acquired from the instructor. Absences involving seeking medical care will require a physician's note. Faculty will follow the CLS Attendance and Participation policy found in the Orientation Handbook. Absences for exams will be docked 10 points at the discretion of the faculty.

Attendance is expected in both lecture and laboratory sessions. In the event of an unavoidable absence, the student must notify the instructor. Students not attending will have points deducted from their attendance and participation grade. In addition, laboratory and small group activities will be completed in class. There will be no makeup for these projects without prior approval from the instructor. It is expected that assignments will be turned in at the beginning of the class period on the due date. Late assignments will have points deducted from them.

Remote Site students: Remote Site students will be expected to routinely check their e-mails. Unless otherwise approved by the faculty, distance students are to take exams, practicals, and quizzes within 1 calendar week of the date assigned for the onsite students.

SAFETY: Students must wear laboratory coats and gloves during laboratory sessions. Shorts and open toed shoes are not allowed. No food or drink will be allowed in the laboratory. All materials must be disposed of properly and tables disinfected before leaving the laboratory. All reusable supplies must be placed on the carts and papers turned in before leaving the laboratory. Keep in mind that your mother doesn't work here.


General Policies of the School of Health Professions

Academic Progress:Information regarding the Student's academic progress in this course will be shared with their Academic Advisor and/or Department Chair. Student's making unsatisfactory progress will be referred to the Office of Student Affairs for assistance.
Academic Integrity:Academic dishonesty includes, but is not limited to, cheating, plagiarism, collusion, the submission for credit of any work or materials that are attributable in whole or in part to another person, taking an examination for another person, and any act designed to give unfair advantage to a student or the attempt to commit such an act. Procedures to be followed in the event of alleged academic dishonesty are described in the Rules and Regulations of the Board of Regents of The University of Texas System, and the SAHS Student Handbook. Alleged academic dishonesty issues should be reported to the Student Affairs Officer.
Professional Behavior:As a part of a professional program, you are expected to conduct yourselves in a manner consistent with the level of trust and responsibility that will be placed on you when you are part of a health care team. You are expected to be honest in your dealings with your instructor and your peers. You are also expected to be able to follow instructions, to act with the utmost integrity, to follow safety protocols while in laboratory, to perform laboratory work with care, and to act in accordance with those standards characteristic of those we call "professionals."
Behavior during examinations, written and practical, will be monitored. Inappropriate behavior may result in pursuance of disciplinary action.
University Statement on Equality, Tolerance, and Affirmative Action:Please indicate by the end of the second week of the semester if you will need accommodations under the Americans with Disabilities Act (Public Law 101-336). If the need for ADA accommodations should arise during the semester you will need to make your request within one week of returning to classes. You may contact your Instructor or the Office of Student Affairs.
Course Evaluation:Students will be given the opportunity to evaluate the instructor and course near the end of the course/semester. When submitting course evaluations students must follow the guidelines provided by the course instructor or the department.
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