Christopher Fry, PhD
Curriculum Vitae Influuent Research Profile PubMed Google Scholar ResearchGate
301 University Blvd.
Galveston, TX 77555-1124
Teaching Areas of Interest
Evidence Based Clinical Practice, Nutrition and Metabolism Seminar
Skeletal muscle physiology, muscle stem cell biology, skeletal muscle plasticity
Christopher Fry, PhD, is an Assistant Professor in the Department of Nutrition & Metabolism in the School of Health Professions (SHP) at the University of Texas Medical Branch (UTMB). Dr. Fry received a Bachelor of Science in Biology from Baylor University, a Doctor of Philosophy degree in Biomedical Sciences from UTMB and completed his Post-Doctoral training in Muscle Physiology at the University of Kentucky. His research interests include aging, nutrition, exercise and muscle physiology.
Dr. Fry's research focuses on elucidating the mechanisms that regulate skeletal muscle plasticity to establish interventions to maintain skeletal muscle mass and strength during conditions of muscle wasting. Much of his current work involves studying the contribution of different progenitor cells to muscle adaptation. Projects in lab include aging muscle growth, muscle recovery following an ACL injury, and interventions to promote restoration of atrophied muscle following a severe burn injury. Dr. Fry's lab utilizes several different experimental models, including cell culture, rodent models as well as muscle samples from clinical studies.
- Fry CS, Johnson DL, Ireland ML, Noehren B. ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle. J Orthop Res. 2016 Dec 9. doi: 10.1002/jor.23502. PMID: 27935172. PMCID: PMC5466509.
- Fry CS, Kirby TJ, Kosmac K, McCarthy JJ, Peterson CA. Satellite cells regulate extracellular matrix remodeling during skeletal muscle adaptation. Cell Stem Cell. 2017 Jan 5;20(1):56-69. PMID: 27840022. PMCID: PMC5218963.
- Kirby TJ, McCarthy JJ, Peterson CA, Fry CS. Synergist ablation as a rodent model to study satellite cell dynamics in adult skeletal muscle. Methods Mol Biol. 2016;1460:43-52. PMID: 27492164.
- Arentson-Lantz E, English KL, Paddon-Jones D, Fry CS. Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults. J Appl Physiol. 2016 Apr 15;120(8):965-75. PMID: 26796754. PMCID: PMC4835912.
- Fry CS, Lee JD, Mula J, Kirby TJ, Jackson JR, Liu F, Yang L, Mendias CL, Dupont-Versteegden EE, McCarthy JJ, Peterson CA. Inducible depletion of satellite cells impairs muscle regenerative capacity without promoting sarcopenia in adult sedentary mice. Nat Med. 2015 Jan; 21(1):76-80. PMID: 25501907. PMCID: PMC4289085.
Note: A complete list of all publications can be found on the abbreviated CV.